Opera Medica et Physiologica

Changes in the Electrical Conductivity of the Myocardium of Isolated Rat Heart Under the Influence of Verapamil

Author Affiliations

E. Kharkovskaia 1, N. Zhidkova 1, I. Mukhina 1,2

1 Lobachevsky State University of Nizhny Novgorod, 23 Gagarina ave., Nizhny Novgorod, Russia, 603950

2 Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia

Corresponding author: 

E. Kharkovskaia (elharkov@gmail.com)


The study was designed to investigate the effect of verapamil on the speed of propagation of electrical excitation in the myocardium. As a result, it was found that verapamil reduces heart rate, the speed of excitation in the myocardium remains unchanged. The results obtained allow us to estimate the effect of verapamil on the condition of cardiac tissue, based on the change in its conductivity during treatment with the drug.