Discovering alternate methods to treat cancer has been the focus of several investigations. The preventive benefits of β-glucan against liver damage, toxicity, and alteration in antinuclear antibody (ANA), alpha-fetoprotein (AFP), and anti-double strand DNA antibody (anti-dsDNA) caused by Ehrlich ascites carcinoma (EAC) are investigated in this study. A total of 40 mice weighing between 20-25 g, were divided randomly into four groups: the control group, the β-glucan group (200 mg/kg bw/day for two weeks), the EAC group, and the EAC+β-glucan group. The most recent research demonstrated that EAC damaged the liver and increased serum levels of AFP, anti-dsDNA, alanine transaminase (ALT), aspartate transaminase (AST), and alkaline phosphatase (ALP). However, compared to the control, serum total proteins and albumin levels considerably decreased. EAC therapy with β-glucan enhanced liver structure and function. As a result, it is possible that suggests that β-glucan can help prevent and treat liver toxicity.
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