Comprehensive Study of Material for Additive Technologies Based on Polymethyl Methacrylate-Like Photopolymer Resin Modified with Metallic Ti Nanoparticles

Methacrylic resins (MAR) are highly sought-after materials for contemporary additive manufacturing of products, exhibiting a broad spectrum of applications. In order to impart new biological properties to the products printed using MSLA-technology, metal titanium nanoparticles (0.001-0.1 w.%) were added to the MAR composition. Samples of composite materials (MAR/Ti-NPs) were printed from the obtained modified resins. The present study demonstrated the ability of the obtained composite materials to enhance the formation of hydroxyl radicals and hydrogen peroxide molecules, to cause oxidative damage to DNA and protein molecules, and to significantly inhibit the growth of E. coli bacterial cultures and cause the death of bacterial cells during prolonged contact with the investigated material samples. The investigations conducted to assess the impact of the obtained composite materials on the proliferation and maturation of HSF cells have indicated an elevated degree of cytocompatibility.