Biomarkers for Predicting the Recovery of Cardiac Activity in Patients Undergoing Coronary Artery Bypass Grafting

During cardiac surgery, as well as on-pump CABG, it is crucial to monitor arterial blood parameters in order to assess the condition of patients and risks that might occur in the operating room. In some cases, the cardiac activity of patients undergoing on-pump CABG cannot be self-restored and resuscitation measures are required. Thus, the aim of the study was to analyze the differences between the two groups of patients (self-restoration of cardiac activity vs additional resuscitation measures were required) and identify arterial blood parameters potentially indicating that the patient is at risk. The data of 21 patients were analyzed with Python packages. Statistically significant differences were found between the control group (self-restoration of cardiac activity) and the test group (additional resuscitation measures were required) in the following arterial blood parameters: the levels of sodium, chloride, glucose and blood osmolality. We believe that hyponatremia and blood hypoosmolality might be a reason for cell edema which creates a greater load on the heart and leads to inability of self-restoration of cardiac activity.