Opera Medica et Physiologica

Analysis of Changes in the Intestinal Microbiota of Patients with Infectious and Somatic Pathology

Abstract: 

The paper presents an analysis of literature data on the characteristics of microbiocenoses across a wide range of infectious and somatic pathologies, as well as the results of our research on changes in the composition of the gastrointestinal tract microbiota in patients with various diseases. It is demonstrated that the microbiota responds consistently to any pathological changes occurring in the host organism, primarily manifested as a disruption in the balance between anaerobic (bifidobacteria, lactobacilli, bacteroids, clostridia, etc.) and aerobic components of the microbiocenosis. The predominance or suppression of specific types of microorganisms is primarily influenced by the composition of the individual's indigenous microbiota, rather than the specific pathology associated with dysbiosis.