Opera Medica et Physiologica

Demographic Analysis of Breast Tumors in a Sample of Iraqi Population

Published ahead of print March 27, 2024; Printed March 28, 2024; OM&P 2024 Volume 11 Issue 1, pages 69-85; doi:10.24412/2500-2295-2024-1-69-85

Breast cancer (BC) is the predominant type of cancer among the female population in Iraq, and one of the most common causes of death among females. Through the period from 2018 until 2020, A total of eighty- two Formalin Fixed-Paraffin embedded FFPE tissue blocks were collected from the archive of Histopathology Department in Teaching Laboratories of Medical City, Teaching Hospital of Al-Yarmouk, and a privately-owned laboratory in Baghdad, Iraq. The clinical information regarding age, gender, tumor size, tumor stage and grade, lymph nodes metastasis, in addition to the findings of estrogen receptor (ER), progesterone receptor (PR) and receptor of human epidermal growth factor (HER)-2 were acquired from carefully reviewing patients' medical records and pathology reports. Results showed that a high incidence of BC in patients at sixth and decades of age, most of tumors′ specimens were within group size of (2-5 cm) in both malignant and benign groups, comprising 57.14% and 80% respectively, the most prevalent histologic type was invasive ductal carcinoma (IDC) encompassing 73.8%. About 59.52% of cases had positive lymph node tumor metastasis, the majority of cases were in grade II 64%. Stage III of the disease had highest rate, most of the cases were ER positive (66%), PR positive (57%) and for the HER most of the cases were HER negative.

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