Opera Medica et Physiologica

Bronchial Asthma and Bilirubin

Published ahead of print March 27, 2024; Printed March 28, 2024; OM&P 2024 Volume 11 Issue 1, pages 115-122; doi:10.24412/2500-2295-2024-1-115-122
Abstract: 

Currently, data are accumulating on the antioxidant properties of bilirubin and its protective role in various diseases. This review considers the dose-dependent effect of bilirubin on its cytoprotective and antioxidant properties, the relationship between the level of bilirubin and the pathophysiological manifestations of bronchial asthma, in the pathogenesis of which chronic inflammation induced by oxidative stress plays a significant role. The article also focuses on the potential therapeutic use of bilirubin in the treatment of bronchial asthma.

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