Opera Medica et Physiologica

Analysis of the Organism Adaptive Reserves of Different Age Groups

Published ahead of print June 04, 2023; Printed June 05, 2023; OM&P 2023 Volume 10 Issue 2, pages 14-23; doi:10.24412/2500-2295-2023-2-14-23
Abstract: 

The article discusses the organism`s adaptive capabilities of different age groups in the population with the use of cardiointervalography and hemodynamic parameters. There was a decrease in the total power of the heart rate variability spectrum and the power of all spectral parameters with an increasing age. In age groups 1 and 2, LF, % and VLF, % were more pronounced, there was a significant predominance of VLF, % in group 2, which reflected an increase in the level of the sympathetic link regulation activity. A more significant increase in the power of very low frequency oscillations indicates an increase in the influence of the central circuit of regulation along with an increase in the cerebral ergotropic influences. Assessment of oxidative metabolism by fluorescence spectroscopy showed an increase in the indicator in group 2, with a tendency to decrease in group 3 as compared to the values of group 1. The performed analysis of the frequency-amplitude spectrum revealed changes in the reactivity of the structures of the microvasculature depending on age. An increase in the volume of blood entering the microcirculation system was recorded, but the regulatory effect on microcirculation was different: group 2 was dominated by central mechanisms of regulation, in group 3 there was a predominance of local regulatory mechanisms. Thus, with age, there is a decrease in the adaptive reserves of the body with a tension in the regulatory vegetative homeostasis and a transition from nervous mechanisms of regulation to a lower level of humoral mechanism.