Opera Medica et Physiologica

E. B. Romanova

Cytogenetic Аpproach to Primary Assessment of Habitat Quality

Anthropogenic environmental pollution reduces the effectiveness of the nervous, immune and endocrine systems. This leads to an increase in chromosomal abnormalities and disrupts the cytogenetic stability of the body. The work has been prompted by the need to identify cytogenetic features of bioindicators reflecting the quality of the habitat. Bioindicators live together with people under the same pollution conditions. They are an important link between human and ecosystem health (Hayes et al., 2002).


Сlassical bioindicators – amphibians – were used to assess the quality of the environment and detect cytogenetic disorders. There are immature erythrocytes with rounded micronuclei in the bone marrow cells. The merging and transformation of micronuclei occurs in the process of mitotic division and erythrocytes maturing. It leads to a prepotency in the bloodstream of erythrocytes with disintegrated micronuclei and an attached micronucleus. An integrated research study of the environment using the cytogenetic characteristics of living organisms is called for.

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